In this enlightening episode, we explore the transformative impact of AI in pharmaceutical R&D with industry experts who unpack the "AI Paradox" - why despite tremendous excitement, many AI initiatives fail to gain traction. We begin by examining the critical role of change management in AI adoption, revealing that 64% of CEOs believe success hinges more on people than technology. The conversation then delves into the emergence of "agentic AI" and its potential to revolutionize clinical trials, followed by an in-depth discussion of decentralized trials (DCTs) and their promise to save clinicians up to 13.5 hours weekly. We also explore a fascinating case study of SI-BONE's differentiation strategy and examine the WHO's 2025 guidance for clinical trial reporting. This episode is essential listening for pharma R&D executives, clinical trial managers, and anyone interested in the intersection of AI and healthcare innovation.
**Highlights:**
[00:00] - Introduction to the AI Paradox in pharmaceutical R&D
[02:16] - Four-phase framework for successful AI change management
[04:57] - Evolution from generative to agentic AI explained
[08:22] - Emerging roles and skills in AI-enabled organizations
[10:08] - HR's critical role in managing AI transformation
[12:06] - Impact and challenges of decentralized clinical trials
[14:07] - WHO 2025 guidance on clinical trial data reporting
[15:30] - SI-BONE case study: Differentiating through evidence generation
[17:11] - Strategic reimbursement and market access insights
[18:40] - Synthesis of key lessons for pharma R&D leadership
[19:36] - Final thoughts on human skills in an AI-powered future
[19:55] - Concluding remarks on balancing technology and human elements
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